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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL17
All Species:
15.76
Human Site:
S518
Identified Species:
31.52
UniProt:
Q6TDP4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.55
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6TDP4
NP_938073.1
642
69874
S518
S
P
V
A
S
M
L
S
R
R
S
S
A
G
V
Chimpanzee
Pan troglodytes
XP_520840
626
68231
K502
S
H
L
A
T
V
E
K
Y
E
P
Q
V
N
V
Rhesus Macaque
Macaca mulatta
XP_001087862
580
62778
R457
S
V
A
S
M
L
S
R
R
S
S
A
G
V
A
Dog
Lupus familis
XP_546727
669
72767
S545
T
P
V
A
S
M
L
S
R
R
S
S
A
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
R481
R
Y
N
P
Q
E
N
R
W
H
T
I
A
P
M
Rat
Rattus norvegicus
Q8K430
640
69714
S516
T
P
V
A
S
M
L
S
R
R
S
S
A
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
R599
R
Y
N
P
Q
E
N
R
W
H
T
I
A
P
M
Chicken
Gallus gallus
XP_417591
590
65056
S466
T
P
I
A
N
M
L
S
R
R
S
S
A
G
V
Frog
Xenopus laevis
Q6NRH0
564
63190
R441
N
I
L
S
S
V
E
R
Y
D
P
H
T
G
H
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
R441
N
I
L
N
S
V
E
R
Y
D
P
H
T
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
T499
V
A
V
S
P
M
S
T
R
R
K
H
L
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794711
642
69880
A512
K
Y
D
P
R
T
N
A
W
T
S
I
P
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
88.6
94.1
N.A.
45.4
97.8
N.A.
42.2
84.2
37.2
36.9
N.A.
44.5
N.A.
N.A.
52.3
Protein Similarity:
100
95
88.9
95.2
N.A.
61
98.5
N.A.
57.3
89.2
53.8
53.2
N.A.
59.3
N.A.
N.A.
70.8
P-Site Identity:
100
20
20
93.3
N.A.
6.6
93.3
N.A.
6.6
80
13.3
13.3
N.A.
33.3
N.A.
N.A.
6.6
P-Site Similarity:
100
40
40
100
N.A.
20
100
N.A.
20
100
40
33.3
N.A.
46.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
42
0
0
0
9
0
0
0
9
50
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
25
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
59
0
% G
% His:
0
9
0
0
0
0
0
0
0
17
0
25
0
0
17
% H
% Ile:
0
17
9
0
0
0
0
0
0
0
0
25
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% K
% Leu:
0
0
25
0
0
9
34
0
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
9
42
0
0
0
0
0
0
0
0
25
% M
% Asn:
17
0
17
9
9
0
25
0
0
0
0
0
0
17
0
% N
% Pro:
0
34
0
25
9
0
0
0
0
0
25
0
9
17
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
17
0
0
0
9
0
0
42
50
42
0
0
0
0
0
% R
% Ser:
25
0
0
25
42
0
17
34
0
9
50
34
0
0
0
% S
% Thr:
25
0
0
0
9
9
0
9
0
9
17
0
17
0
0
% T
% Val:
9
9
34
0
0
25
0
0
0
0
0
0
9
9
42
% V
% Trp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% W
% Tyr:
0
25
0
0
0
0
0
0
25
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _